About 18 to 25 % of levopimaric acid is found in pine oleoresin.
2.
Levopimaric acid can be extracted by dissolving longleaf pine oleoresin in acetone and then adding 2-amino-2-methyl-1-propanol.
3.
The abietane skeleton of levopimaric acid is formed by the cyclization of a diterpenoid precursor, ( + )-copalyl diphosphate, goes through the oxidation and rearrangement to give the intermediate ( c ), levopimaradiene, and diphosphate molecule.
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